The hepatic cytochrome P450 (CYP) enzyme technique is involved with SC metabolism. JWH-018 and AM-2201 (its fluorinated analogue) are metabolized inside the liver by CYP2C9 and 1A2. So, there is the likely to bring about AE when given concurrently with medicines including valproic acid, warfarin, phenytoin, and ciprofloxacin. CYP2C9 can also be cur